Article
HLA-G and IL-10 in serum in relation to HLA-G genotype and polymorphisms.
Immunogenetics - 1 Jun 2004
Hviid Thomas Vauvert F, Rizzo Roberta, Christiansen Ole B, Melchiorri Loredana, Lindhard Anette, Baricordi Olavio R
Abstract excerpt
The expression and importance of the non-classical human leukocyte antigen (HLA) class Ib gene, HLA-G, at the feto-maternal interface have been recognized. The HLA-G molecule is almost monomorphic and expressed in both membrane-bound and soluble isoforms. It has been shown to inhibit NK-mediated cell lysis and influence cytokine expression. Recently, a possible boarder immunoregulatory function of HLA-G also in...
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