Article
HLA-G haplotype structure shows good conservation between different populations and good correlation with high, normal and low soluble HLA-G expression.
Human immunology - 1 Feb 2013
Di Cristofaro Julie, El Moujally Dima, Agnel Anaïs, Mazières Stéphane, Cortey Martí, Basire Agnès, Chiaroni Jacques, Picard Christophe
Abstract excerpt
HLA-G molecule has considerable impact in various clinical fields, therefore many studies attempted to predict its expression based on HLA-G genotype. These studies have focused on polymorphisms in either the coding region or in one of the two untranslated regions (UTR) of the gene. The aim of our study was to determine if HLA-G haplotype defined based on SNPs 5' and 3'UTR could be used to predict soluble HLA-G...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.