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Article

Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering.

The Journal of pathology - 1 Apr 2014

Kopecki Zlatko, Yang Gink N, Arkell Ruth M, Jackson Jessica E, Melville Elizabeth, Iwata Hiroaki, Ludwig Ralf J, Zillikens Detlef, Murrell Dedee F, Cowin Allison J

Abstract excerpt

Development of an intact epidermis is critical for maintaining the integrity of the skin. Patients with epidermolysis bullosa (EB) experience multiple erosions, which breach the epidermal barrier and lead to increased microbial colocalization of wounds, infections and sepsis. The cytoskeletal pro...

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Source

Identifiers

PMID: 24375017
DOI: 10.1002/path.4323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24375017-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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