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Article

Disorders of the cutaneous basement membrane zone--the paradigm of epidermolysis bullosa.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jan 2014

Bruckner-Tuderman Leena, Has Cristina

Abstract excerpt

The cutaneous basement membrane zone (BMZ) is a highly specialized functional complex that provides the skin with structural adhesion and resistance to shearing forces. Its regulatory functions include control of epithelial-mesenchymal interactions under physiological and pathological conditions. Mutations in genes encoding components of the BMZ are associated with inherited skin disorders of the epidermolysis...

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Identifiers

PMID: 23917088
DOI: 10.1016/j.matbio.2013.07.007

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