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Telomere Length Maintenance, Shortening, and Lengthening

21 Dec 2013

Abstract excerpt

Telomeres maintain chromosome stability and cell replicative capacity. Telomere shortening occurs concomitant with aging. Short telomeres are associated with some diseases, such as dyskeratosis congenita, idiopathic pulmonary fibrosis, and aplastic anemia. Telomeres are longer in pluripotent stem cells than in somatic cells and lengthen significantly during preimplantation development. Furthermore, telomere...

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PMID: 24374808
DOI: 10.1002/jcp.24537

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