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Article

Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.

Cell reports - 16 Jan 2014

Madzo Jozef, Liu Hui, Rodriguez Alexis, Vasanthakumar Aparna, Sundaravel Sriram, Caces Donne Bennett D, Looney Timothy J, Zhang Li, Lepore Janet B, Macrae Trisha, Duszynski Robert, Shih Alan H, Song Chun-Xiao, Yu Miao, Yu Yiting, Grossman Robert, Raumann Brigitte, Verma Amit, He Chuan, Levine Ross L, Lavelle Don, Lahn Bruce T, Wickrema Amittha, Godley Lucy A

Abstract excerpt

Hematopoietic stem cell differentiation involves the silencing of self-renewal genes and induction of a specific transcriptional program. Identification of multiple covalent cytosine modifications raises the question of how these derivatized bases influence stem cell commitment. Using a replicati...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24373966
DOI: 10.1016/j.celrep.2013.11.044
PMCID: PMC3976649

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24373966-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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