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Article

Susceptibility to glaucoma damage related to age and connective tissue mutations in mice.

Experimental eye research - 1 Feb 2014

Steinhart Matthew R, Cone-Kimball Elizabeth, Nguyen Cathy, Nguyen Thao D, Pease Mary E, Chakravarti Shukti, Oglesby Ericka N, Quigley Harry A

Abstract excerpt

The purpose of this research was to study the effects of age and genetic alterations in key connective tissue proteins on susceptibility to experimental glaucoma in mice. We used mice haploinsufficient in the elastin gene (EH) and mice without both alleles of the fibromodulin gene (FM KO) and their wild type (WT) littermates of B6 and CD1 strains, respectively. FM KO mice were tested at two ages: 2 months and 12...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24368172
DOI: 10.1016/j.exer.2013.12.008
PMCID: PMC3967240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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