Article
Differential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush.
BMC neuroscience - 30 Jul 2009
Templeton Justin P, Nassr Mohamed, Vazquez-Chona Felix, Freeman-Anderson Natalie E, Orr William E, Williams Robert W, Geisert Eldon E
Abstract excerpt
BACKGROUND: Retinal ganglion cell (RGC) death is the final consequence of many blinding diseases, where there is considerable variation in the time course and severity of RGC loss. Indeed, this process appears to be influenced by a wide variety of genetic and environmental factors. In this study we explored the genetic basis for differences in ganglion cell death in two inbred strains of mice. RESULTS: We found...
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