Article
Polymorphisms of the Costimulatory Genes CTLA-4, CD28, PD-1, and ICOS and Outcome of Kidney Transplants in Iranian Patients.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Jun 2017
Niknam Ahmad, Karimi Mohammad Hossein, Geramizadeh Bita, Roozbeh Jamshid, Yaghobi Ramin, Salehipour Mehdi
Abstract excerpt
OBJECTIVES: Costimulatory molecules are important factors determining the outcome of transplant. The aim of the present study was to investigate the effect of CTLA-4, CD28, PD-1, and ICOS gene polymorphisms on the outcome of kidney transplant. MATERIALS AND METHODS: A total of 172 kidney transplant recipients were included in this study. There were 45 recipients (26%) who experienced acute rejection. The CTLA-4,...
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