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Article

Association of genetic variation in inducible costimulator gene with outcome of kidney transplantation.

Transplantation - 15 Feb 2009

Haimila Katri, Turpeinen Hannu, Alakulppi Noora S, Kyllönen Lauri E, Salmela Kaija T, Partanen Jukka

Abstract excerpt

BACKGROUND: The closely-linked genes of CD28, cytotoxic T-lymphocyte associated antigen 4 (CTLA4), inducible costimulator (ICOS), and programmed cell death 1 on chromosome 2q encode costimulatory molecules, which are regulators of the T-cell activity. The T-cell mediated immune response has a major role in allograft rejection. Hence, the variation in these genes may have an effect on graft survival and the amount...

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Share to Antigens, Differentiation, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 2

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Source

Identifiers

PMID: 19202444
DOI: 10.1097/TP.0b013e318192897a

Genes

ICOS
CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Association of genetic variation in inducible costimulator gene with outcome of kidney transplantation.PMID 19202444Read ↗

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