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Article

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition

24 Dec 2013

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transition (EMT) is known to impart metastasis and stemness characteristics in breast cancer. To characterize the epigenetic reprogramming following Twist1-induced EMT, we characterized the epigenetic and transcriptome landscapes using whole-genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of methylation (DREAM) and histone...

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PMID: 24367927
DOI: 10.1186/gb-2013-14-12-r144

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