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Article

Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition

2 Sept 2013

Abstract excerpt

BACKGROUND: The epithelial-mesenchymal transition (EMT) is a de-differentiation process required for wound healing and development. In tumors of epithelial origin aberrant induction of EMT contributes to cancer progression and metastasis. Studies have begun to implicate epigenetic reprogramming in EMT; however, the relationship between reprogramming and the coordination of cellular processes is largely...

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PMID: 24004852
DOI: 10.1186/1756-8935-6-28

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