Article
Novel single nucleotide polymorphism markers for low dose aspirin-associated small bowel bleeding.
PloS one - 1 Jan 2013
Shiotani Akiko, Murao Takahisa, Fujita Yoshihiko, Fujimura Yoshinori, Sakakibara Takashi, Nishio Kazuto, Haruma Ken
Abstract excerpt
BACKGROUND: Aspirin-induced enteropathy is now increasingly being recognized although the pathogenesis of small intestinal damage induced by aspirin is not well understood and related risk factors have not been established. AIM: To investigate pharmacogenomic profile of low dose aspirin (LDA)-induced small bowel bleeding. METHODS: Genome-wide analysis of single nucleotide polymorphisms (SNPs) was performed using...
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