Article
Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes' polymorphism.
Digestive diseases and sciences - 1 Feb 2011
Shiotani Akiko, Nishi Ryuji, Yamanaka Yoshiyuki, Murao Takahisa, Matsumoto Hiroshi, Tarumi Ken-ichi, Kamada Tomoari, Sakakibara Takashi, Haruma Ken
Abstract excerpt
BACKGROUND: We have previously shown that co-treatment of angiotensin type 1 receptor (AT1R) blocker (ARB) or angiotensin converting enzyme (ACE) inhibitor seem to reduce peptic ulcer among patients taking low dose aspirin. It is reported that a series of renin-angiotensin system (RAS) gene polymorphisms significantly influence the rate of the gene transcription. AIM: The aim of this study was to examine the...
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