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Article

Genetic polymorphisms associated with upper gastrointestinal bleeding: a systematic review.

The pharmacogenomics journal - 1 Feb 2021

Forgerini Marcela, Lucchetta Rosa Camila, Urbano Gustavo, de Nadai Tales Rubens, de Carvalho Mastroianni Patrícia

Abstract excerpt

Non-variceal upper gastrointestinal bleeding (non-variceal UGIB) is a frequent and severe adverse drug reaction. Idiosyncratic responses due to genetic susceptibility to non-variceal UGIB has been suggested. A systematic review was conducted to assess the association between genetic polymorphisms and non-variceal UGIB. Twenty-one publications and 7134 participants were included. Thirteen studies evaluated genetic...

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Identifiers

PMID: 32948830
DOI: 10.1038/s41397-020-00185-6

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