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Article

A novel gene associated with small bowel bleeding in patients taking low-dose aspirin.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2021

Handa Yukiko, Fukushima Shinya, Yo Shogen, Osawa Motoyasu, Murao Takahisa, Handa Osamu, Matsumoto Hiroshi, Umegaki Eiji, Sakakibara Takashi, Shiotani Akiko

Abstract excerpt

OBJECTIVE: We have previously revealed the clinical factors and genetic polymorphisms associated with gastrointestinal mucosal injury and bleeding, induced by low-dose aspirin (LDA). After performing genome-wide analysis of single nucleotide polymorphisms (SNPs) using the Drug Metabolizing Enzymes and Transporters (DMET) system among drug metabolism and transporter genes, certain SNPs were found to increase the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34059446
DOI: 10.1016/j.dld.2021.04.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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