Article
Copy number variations of HLA-DRB5 is associated with systemic lupus erythematosus risk in Chinese Han population.
Acta biochimica et biophysica Sinica - 1 Feb 2014
Wu Lijun, Guo Shicheng, Yang Dongqin, Ma Yanyun, Ji Hengdong, Chen Yulin, Zhang Jun, Wang Yi, Jin Li, Wang Jiucun, Liu Jie
Abstract excerpt
Systemic lupus erythematosus (SLE) is a polygenic, systemic, autoimmune disease. Copy number variants (CNVS) have been discovered to be associated with a number of complex disorders. We undertook the current study to explore the potential associations between genomic CNVS and SLE in Chinese Han population. In the discovery stage, seven SLE patients were examined with the high-density comparative genomic...
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