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Article

Association of VPREB1 Gene Copy Number Variation and Rheumatoid Arthritis Susceptibility.

Disease markers - 1 Jan 2020

Aslam Muhammad Muaaz, John Peter, Fan Kang-Hsien, Bhatti Attya, Feingold Eleanor, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

OBJECTIVE: Copy number variation (CNV) is a structural variation in the human genome that has been associated with multiple clinical phenotypes. B cells are important components of rheumatoid arthritis- (RA-) mediated immune response; hence, CNV in the regulators of B cells (such as VPREB1) can influence RA susceptibility. In this study, we aimed to explore the association of CNV in the VPREB1 gene with RA...

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Arthritis, Rheumatoid
Case-Control Studies
DNA Copy Number Variations
Genetic Predisposition to Disease
Pakistan

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PMID: 33101545
DOI: 10.1155/2020/7189626
PMCID: PMC7568136

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