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Article

Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.

Journal of human genetics - 1 Jan 2008

Kamatani Yoichiro, Matsuda Koichi, Ohishi Tetsuya, Ohtsubo Shigeru, Yamazaki Keiko, Iida Aritoshi, Hosono Naoya, Kubo Michiaki, Yumura Wako, Nitta Kosaku, Katagiri Toyomasa, Kawaguchi Yasushi, Kamatani Naoyuki, Nakamura Yusuke

Abstract excerpt

Systemic lupus erythematosus (SLE) is one of the common autoimmune diseases, with complex genetic components. Here, we report on a case-control association study of 178 SLE patients and 899 control subjects, using genome-wide gene-based single nucleotide polymorphism (SNP) markers. An SNP, rs3130342, in a 5' flanking region of the TNXB gene revealed a significant association with SLE [P = 0.000000930, odds ratio...

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Source

Identifiers

PMID: 18058064
DOI: 10.1007/s10038-007-0219-1

Genes

TNXB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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