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Article

Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.

Prostate cancer and prostatic diseases - 1 Mar 2014

Van Allen E M, Foye A, Wagle N, Kim W, Carter S L, McKenna A, Simko J P, Garraway L A, Febbo P G

Abstract excerpt

BACKGROUND: Comprehensive molecular characterization of cancer that has metastasized to bone has proved challenging, which may limit the diagnostic and potential therapeutic opportunities for patients with bone-only metastatic disease. METHODS: We describe successful tissue acquisition, DNA extraction, and whole-exome sequencing from a bone metastasis of a patient with metastatic, castration-resistant prostate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24366412
DOI: 10.1038/pcan.2013.37
PMCID: PMC4364998

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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