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SIUrO best practice recommendations to optimize BRCA 1/2 gene testing from DNA extracted from bone biopsy in mCRPC patients (BRCA Optimal Bone Biopsy Procedure: BOP).

Virchows Archiv : an international journal of pathology - 1 Nov 2023

Cimadamore Alessia, Rescigno Pasquale, Conteduca Vincenza, Caliò Anna, Allegritti Massimiliano, Calò Valentina, Montagnani Ilaria, Lucianò Roberta, Patruno Margherita, Bracarda Sergio

Abstract excerpt

The main guidelines and recommendations for the implementation of the BRCA1/2 somatic test do not focus on the clinical application of predictive testing on bone metastases, a frequent condition in metastatic prostate cancer, by analyzing the critical issues encountered by laboratory practice. Our goal is to produce a document (protocol) deriving from a multidisciplinary team approach to obtain high quality...

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PMID: 37794204
DOI: 10.1007/s00428-023-03660-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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