Article
Pertactin-negative variants of Bordetella pertussis in New York State: a retrospective analysis, 2004-2013.
Molecular and cellular probes - 1 Aug 2014
Quinlan Tammy, Musser Kimberlee A, Currenti Salvatore A, Zansky Shelley M, Halse Tanya A
Abstract excerpt
The first report of pertactin-negative variants of Bordetella pertussis in the United States has raised questions about the role of acellular pertussis vaccines in the recent increase of pertussis cases. Our laboratory utilized a sequence-based method to identify mutations in the pertactin gene responsible for these variants and assessed vaccination status from the associated cases.
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