Article
Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines.
Microbial genomics - 1 May 2018
Zomer Aldert, Otsuka Nao, Hiramatsu Yukihiro, Kamachi Kazunari, Nishimura Naoko, Ozaki Takao, Poolman Jan, Geurtsen Jeroen
Abstract excerpt
Bordetella pertussis, the causative agent of whooping cough, has experienced a resurgence in the past 15 years, despite the existence of both whole-cell and acellular vaccines. Here, we performed whole genome sequencing analysis of 149 clinical strains, provided by the National Institute of Infectious Diseases (NIID), Japan, isolated in 1982-2014, after Japan became the first country to adopt acellular vaccines...
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