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Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications

21 Dec 2015

Abstract excerpt

Melanocytes in the skin play an indispensable role in the pigmentation of skin and its appendages. It is well known that the embryonic origin of melanocytes is neural crest cells. In adult skin, functional melanocytes are continuously repopulated by the differentiation of melanocyte stem cells (McSCs) residing in the epidermis of the skin. Many preceding studies have led to significant discoveries regarding the...

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PMID: 26703580
DOI: 10.3390/ijms161226207

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