Article
Phenotypic plasticity of melanocytes derived from human adult skin.
Pigment cell & melanoma research - 1 Jan 2022
Vidács Dániel László, Veréb Zoltán, Bozó Renáta, Flink Lili Borbála, Polyánka Hilda, Németh István Balázs, Póliska Szilárd, Papp Benjamin Tamás, Manczinger Máté, Gáspár Róbert, Mirdamadi Seyedmohsen, Kemény Lajos, Bata-Csörgő Zsuzsanna
Abstract excerpt
We previously described a novel in vitro culture technique for dedifferentiated human adult skin melanocytes. Melanocytes cultured in a defined, cholera toxin and PMA free medium became bipolar, unpigmented, and highly proliferative. Furthermore, TRP-1 and c-Kit expression disappeared and EGFR receptor and nestin expression were induced in the cells. Here, we further characterized the phenotype of these...
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