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Article

Generation of Human Melanocytes from Induced Pluripotent Stem Cells

13 Jan 2011

Abstract excerpt

Epidermal melanocytes play an important role in protecting the skin from UV rays, and their functional impairment results in pigment disorders. Additionally, melanomas are considered to arise from mutations that accumulate in melanocyte stem cells. The mechanisms underlying melanocyte differentiation and the defining characteristics of melanocyte stem cells in humans are, however, largely unknown. In the present...

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PMID: 21249204
DOI: 10.1371/journal.pone.0016182

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