Article
Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI.
Diabetologia - 1 Apr 2014
Bailey Swneke D, Xie Changchun, Paré Guillaume, Montpetit Alexandre, Mohan Viswanathan, Yusuf Salim, Gerstein Hertzel, Engert James C, Anand Sonia S
Abstract excerpt
AIMS/HYPOTHESIS: Dyslipidaemia, a common feature of type 2 diabetes, is characterised by an increase in atherogenic particles, quantifiable through apolipoprotein B (ApoB) levels. Genetic studies of lipid levels have focused on Europeans; a study in South Asians could identify novel genes. METHODS: We tested 31,739 single nucleotide polymorphisms (SNPs) from ∼ 2,000 genes in 2,573 South Asians from the...
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