Article
An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference.
Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2011
Rees S D, Islam M, Hydrie M Z I, Chaudhary B, Bellary S, Hashmi S, O'Hare J P, Kumar S, Sanghera D K, Chaturvedi N, Barnett A H, Shera A S, Weedon M N, Basit A, Frayling T M, Kelly M A, Jafar T H
Abstract excerpt
AIMS: A common variant, rs9939609, in the FTO (fat mass and obesity) gene is associated with adiposity in Europeans, explaining its relationship with diabetes. However, data are inconsistent in South Asians. Our aim was to investigate the association of the FTO rs9939609 variant with obesity, obesity-related traits and Type 2 diabetes in South Asian individuals, and to use meta-analyses to attempt to clarify to...
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