Article
Association analysis of putative cis-acting polymorphisms of interleukin-19 gene with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Apr 2014
Okazaki Satoshi, Watanabe Yuichiro, Hishimoto Akitoyo, Sasada Toru, Mouri Kentaro, Shiroiwa Kyoichi, Eguchi Noriomi, Ratta-Apha Woraphat, Otsuka Ikuo, Nunokawa Ayako, Kaneko Naoshi, Shibuya Masako, Someya Toshiyuki, Shirakawa Osamu, Sora Ichiro
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) and gene expression analyses have revealed that single nucleotide polymorphisms (SNPs) associated with multifactorial diseases, such as schizophrenia, are significantly more likely to be associated with expression quantitative trait loci (eQTL). It was recently suggested that an immune system imbalance plays an important role in the pathogenesis of schizophrenia....
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