Article
Role of IL-6/RORC/IL-22 axis in driving Th17 pathway mediated immunopathogenesis of schizophrenia.
Cytokine - 1 Nov 2018
Subbanna Manjula, Shivakumar Venkataram, Talukdar Pinku Mani, Narayanaswamy Janardhanan C, Venugopal Deepthi, Berk Michael, Varambally Shivarama, Venkatasubramanian Ganesan, Debnath Monojit
Abstract excerpt
The immuno-inflammatory origin of schizophrenia in a subset of patients is viewed as a key element of an overarching etiological construct. Despite substantial research, the immune components exerting major effect are yet to be fully clarified. Disrupted T cell networks have consistently been linked to the pathogenesis of schizophrenia. Amongst the Th cell subsets, the Th17 cells have emerged as a paradigmatic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.