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Article

Variants of Th17 pathway-related genes influence brain morphometric changes and the risk of schizophrenia through epistatic interactions.

Psychiatric genetics - 1 Aug 2022

Subbanna Manjula, Shivakumar Venkataram, Bhalerao Gaurav, Varambally Shivarama, Venkatasubramanian Ganesan, Debnath Monojit

Abstract excerpt

OBJECTIVE: T helper 17 (Th17) pathway has been reported to be abnormal in schizophrenia; however, it is not known whether variation within genes of this pathway has any impact on schizophrenia. Herein, the impact of genetic variations and gene-gene interactions of Th17 pathway-related genes on the risk, psychopathology, and brain volume was examined in schizophrenia patients. METHODS: Functional polymorphisms...

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Identifiers

PMID: 35353801
DOI: 10.1097/YPG.0000000000000315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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