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Article

RAS, BRAF, and TP53 gene mutations in Taiwanese colorectal cancer patients.

Onkologie - 1 Jan 2013

Chang Ya-Sian, Chang Shun-Jen, Yeh Kun-Tu, Lin Tsai-Hsiu, Chang Jan-Gowth

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) plays an important role in cancer mortality and morbidity. This study examined colorectal tissues for RAS, BRAF, and TP53 gene mutations to assess their value as indicators of outcomes of CRC therapy. MATERIAL AND METHODS: DNA was extracted from tissues taken from 165 patients with CRC. RAS gene mutations (exons 2 and 3) were detected by primer extension analysis. BRAF gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24356563
DOI: 10.1159/000356814

Genes

BRAF
KRAS

Variants

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