Article
Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila.
PloS one - 1 Jan 2011
Fitzsimons Helen L, Scott Maxwell J
Abstract excerpt
There is increasing evidence that regulation of local chromatin structure is a critical mechanism underlying the consolidation of long-term memory (LTM), however considerably less is understood about the specific mechanisms by which these epigenetic effects are mediated. Furthermore, the importance of histone acetylation in Drosophila memory has not been reported. The histone deacetylase (HDAC) Rpd3 is abundant...
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