Article
KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.
PloS one - 1 Jan 2013
Murdock Deborah G, Bradford Yuki, Schnetz-Boutaud Nathalie, Mayo Ping, Allen Melissa J, D'Aoust Laura N, Liang Xueying, Mitchell Sabrina L, Zuchner Stephan, Small Gary W, Gilbert John R, Pericak-Vance Margaret A, Haines Jonathan L
Abstract excerpt
Alzheimer disease (AD) is a devastating neurodegenerative disease affecting more than five million Americans. In this study, we have used updated genetic linkage data from chromosome 10 in combination with expression data from serial analysis of gene expression to choose a new set of thirteen candidate genes for genetic analysis in late onset Alzheimer disease (LOAD). Results in this study identify the KIAA1462...
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