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Article

DNA methylation of antisense noncoding RNA in the INK locus (ANRIL) is associated with coronary artery disease in a Chinese population.

Scientific reports - 25 Oct 2019

Zhao Chen-Hui, Cao Hai-Tao, Zhang Jing, Jia Qiao-Wei, An Feng-Hui, Chen Zhao-Hong, Li Li-Hua, Wang Lian-Sheng, Ma Wen-Zhu, Yang Zhi-Jian, Jia En-Zhi

Abstract excerpt

To explore the association between methylation of antisense non-coding RNA in the INK4 locus (ANRIL) and coronary artery disease (CAD) development. Methylation levels of ANRIL in 100 subjects with CAD and 100 controls were quantitatively analyzed using Sequenom MassARRAY. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was used to identify novel pathways. Our analyses indicated that 7...

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PMID: 31653960
DOI: 10.1038/s41598-019-51921-3
PMCID: PMC6814794

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