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Increased DNA and RNA damage by oxidation in patients with bipolar I disorder

9 Aug 2016

Abstract excerpt

The mechanisms underlying bipolar disorder (BD) and the associated medical burden are unclear. Damage generated by oxidation of nucleosides may be implicated in BD pathophysiology; however, evidence from in vivo studies is limited and the extent of state-related alterations is unclear. This prospective study investigated for we believe the first time the damage generated by oxidation of DNA and RNA strictly in...

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PMID: 27505230
DOI: 10.1038/tp.2016.141

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