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Mitochondrial DNA copy number is significantly increased in bipolar disorder patients and is correlated with long-term lithium treatment

28 Nov 2024

Abstract excerpt

• BD has been previously associated with altered mitochondrial functioning. • The role of mitochondrial response to medication is still unclear. • In the current study, mtDNA-cn, a biomarker of mitochondrial function, was higher in BD compared to controls. • mtDNA-cn in lithium-treated patients resulted comparable to controls. • Treatment with mood stabilizers other than lithium did not show any correlation with...

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Bipolar Disorder and Treatment
Genetics and Neurodevelopmental Disorders
Tryptophan and brain disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39612728
DOI: 10.1016/j.euroneuro.2024.10.012

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