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Article

The V(H) repertoire and clonal diversification of B cells in inflammatory myopathies.

European journal of immunology - 1 Feb 2014

McIntyre Donna, Zuckerman Neta S, Field Max, Mehr Ramit, Stott David I

Abstract excerpt

The contribution of antigen-driven B-cell adaptive immune responses within the inflamed muscle of inflammatory myopathies (IMs) is largely unknown. In this study, we investigated the immunoglobulin V(H) gene repertoire, somatic hypermutation, clonal diversification, and selection of infiltrating B cells in muscle biopsies from IM patients (dermatomyositis and polymyositis), to determine whether B cells and/or...

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Identifiers

PMID: 24343314
DOI: 10.1002/eji.201343315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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