Article

Epigenetic dysregulation of Th2 cytokine genes in MuSK myasthenia gravis and its modulation by immunosuppressive therapy

2026-08-11

Abstract excerpt

<h4>Background and objectives</h4> Myasthenia gravis associated with antibodies against muscle-specific kinase (MuSK-MG) is a well-characterized IgG4-autoimmune disease, however, the mechanisms driving IgG4 predominance remain poorly understood. This study investigated whether promoter DNA methylation of cytokine genes involved in IgG4 class switching is associated with this immune response. <h4>Methods</h4> Per...

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Literature Corpus work: e4d5b44c-1269-5740-9617-cb35dc56ab48
DOI: 10.64898/2026.08.05.742975

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