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Identification of distinctive interferon gene signatures in different types of myositis

22 Aug 2019

Abstract excerpt

Objective Activation of the type 1 interferon (IFN1) pathway is a prominent feature of dermatomyositis (DM) muscle and may play a role in the pathogenesis of this disease. However, the relevance of the IFN1 pathway in patients with other types of myositis such as the antisynthetase syndrome (AS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM) is largely unknown. Moreover, the...

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PMID: 31434690
DOI: 10.1212/wnl.0000000000008128

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