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Article

SCN1A variations and response to multiple antiepileptic drugs.

The pharmacogenomics journal - 1 Aug 2014

Yip T S C, O'Doherty C, Tan N C K, Dibbens L M, Suppiah V

Abstract excerpt

In the current study, we have used the haplotype-tagging single-nucleotide polymorphisms (SNPs) to determine associations between genetic variants in SCN1A and treatment response in 519 Caucasian patients with known response status for epilepsy treated with antiepileptic drugs (AEDs) with sodium channel blocking effects. Nine SNPs within SCN1A were genotyped in this cohort. The only association observed was for...

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Identifiers

PMID: 24342961
DOI: 10.1038/tpj.2013.43

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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