Article
[The first experience of application of standardized genotype technique of identification of HIV-tropism].
Klinicheskaia laboratornaia diagnostika - 1 Jun 2013
Lopatukhin A É, Kireev D E, Poliakov A N, Bukin E K, Kaiser R, Luebke N, Kuevda D A, Shipulin G A
Abstract excerpt
The antagonists of co-receptor CCR5 are an ultimately new class of preparations to treat HIV-infection. The mechanism of action of the preparations of this class is in the selective binding with co-receptor CCR5. This process results in the prevention of penetration of HIV into cell. Before prescribing the CCR5 antagonists the detection of viral tropism has to be done. Recently, in Russia the genotype technique...
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