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Article

The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment.

Blood - 5 Sept 2013

Gotlib Jason, Maxson Julia E, George Tracy I, Tyner Jeffrey W

Abstract excerpt

Although activation of tyrosine kinase pathways is a shared theme among myeloproliferative neoplasms, the pathogenetic basis of chronic neutrophilic leukemia (CNL) has remained elusive. Recently, we identified high-frequency oncogenic mutations in the granulocyte-colony stimulating factor receptor (CSF3R) in CNL and in some patients with atypical chronic myeloid leukemia. Inhibition of Janus kinase 2 or SRC...

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Identifiers

PMID: 23896413
DOI: 10.1182/blood-2013-05-500959
PMCID: PMC3765056

Genes

SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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