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Article

Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the β-Catenin/TCF/LEF-1 pathway in gastric cancer cells.

Nucleic acids research - 1 Mar 2014

Tang Xiaoli, Zheng Dong, Hu Ping, Zeng Zongyue, Li Ming, Tucker Lynne, Monahan Renee, Resnick Murray B, Liu Manran, Ramratnam Bharat

Abstract excerpt

Glycogen synthase kinase 3 beta (GSK3β) is a critical protein kinase that phosphorylates numerous proteins in cells and thereby impacts multiple pathways including the β-Catenin/TCF/LEF-1 pathway. MicroRNAs (miRs) are a class of noncoding small RNAs of ∼22 nucleotides in length. Both GSK3β and miR play myriad roles in cell functions including stem cell development, apoptosis, embryogenesis and tumorigenesis. Here...

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Identifiers

PMID: 24335145
DOI: 10.1093/nar/gkt1275
PMCID: PMC3950676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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