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Article

Transcription factor C/EBPβ and 17β-estradiol promote transcription of the porcine p53 gene.

The international journal of biochemistry & cell biology - 1 Feb 2014

Tao Hu, Mei Shuqi, Zhang Xuying, Peng Xianwen, Yang Jiahao, Zhu Lihua, Zhou Jiawei, Wu Huayu, Wang Lei, Hua Lun, Li Fenge

Abstract excerpt

The tumor protein 53 (p53) gene played a crucial role in maternal reproduction except its classic roles in maintaining genomic stability and preventing tumorigenesis. However, little is known concerning the regulatory elements which control the expression of p53 gene. In this study, we predicted two binding sites (-490/-477 and -405/-392) of transcription factor CCAAT/enhancer binding protein beta (C/EBPβ) within...

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PMID: 24333671
DOI: 10.1016/j.biocel.2013.12.002

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