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Article

[The role of p53 binding site on the trans binding of p53 to Hsp90 beta gene].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Jun 2002

Chen Li-ling, Wu Ning-hua, Shen Yu-fei, Guan Xin-min

Abstract excerpt

OBJECTIVE: To investigate the effect of p53 binding site (+31/+60) of hsp90 beta gene on its transcriptional regulation. METHODS: The binding site was first inserted into pBS-SK. After the plasmid annealing and elongation with mutagenic and selective primers, nuclease digestion and bacteria transformation was performed twice to select the positive mutated plasmid. Electrophoretic mobility shift assays (EMSA) was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12905636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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