Article
Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans.
Cell biochemistry and function - 1 Jan 2000
Mendoza-Cantú Ania, Castorena-Torres Fabiola, Bermudez Mario, Martínez-Hernández Roberto, Ortega Arturo, Salinas Juan E, Albores Arnulfo
Abstract excerpt
CYP1A2 and CYP2E1 are two of the main cytochrome P450 isoforms involved in the metabolism of commonly used drugs and xenobiotic compounds considered to be responsible for or possible participants in the development of several human diseases. Individual susceptibility to developing these pathologies relies, among other factors, on genetic polymorphism which depends on ethnic differences, as the frequency of mutant...
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