Article
Breaking symmetry: a clinical overview of left-right patterning.
Clinical genetics - 1 Jun 2004
Maclean K, Dunwoodie S L
Abstract excerpt
It is increasingly recognized that mutations in genes and pathways critical for left-right (L-R) patterning are involved in common isolated congenital malformations such as congenital heart disease, biliary tract anomalies, renal polycystic disease, and malrotation of the intestine, indicating that disorders of L-R development are far more common than a 1 in 10,000 incidence of heterotaxia might suggest....
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