Interactive effects of DRD2 rs6277 polymorphism, environment and sex on impulsivity in a population-representative study.

doi:10.1016/j.bbr.2021.113131

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Article

Interactive effects of DRD2 rs6277 polymorphism, environment and sex on impulsivity in a population-representative study.

Behavioural brain research - 9 Apr 2021

Klaus K, Vaht M, Pennington K, Harro J

Abstract excerpt

Previous research has shown that dopaminergic dysregulation and early life stress interact to impact on aspects of impulse control. This study aimed to explore the potentially interactive effects of the rs6277 polymorphism of the dopamine D2 receptor gene (DRD2), stressful or supportive environment and sex on behavioural and self-reported measures of impulsivity, as well as alcohol use - a condition characterised...

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PMID: 33444693
DOI: 10.1016/j.bbr.2021.113131

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