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Article

Mitochondrial dysfunction in gliomas.

Seminars in pediatric neurology - 1 Sept 2013

Katsetos Christos D, Anni Helen, Dráber Pavel

Abstract excerpt

Mitochondrial (mt) dysfunction in gliomas has been linked to abnormalities of mt energy metabolism, marked by a metabolic shift from oxidative phosphorylation to glycolysis ("Warburg effect"), disturbances in mt membrane potential regulation and apoptotic signaling, as well as to somatic mutations involving the Krebs cycle enzyme isocitrate dehydrogenase. Evolving biological concepts with potential therapeutic...

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Identifiers

PMID: 24331363
DOI: 10.1016/j.spen.2013.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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